Symbol
Name
ID

Clcn2
chloride channel, voltage-sensitive 2
MGI:105061

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Adrenal hyperplasia	Decreased circulating renin level	Hyperaldosteronism
Disease(s) Associated with CLCN2
primary hyperaldosteronism

Mouse Phenotypes

abnormal salivary gland physiology

endocrine/exocrine gland phenotype

abnormal testis morphology

abnormal seminiferous tubule morphology

abnormal Sertoli cell morphology

seminiferous tubule degeneration

abnormal testis development

abnormal Sertoli cell development

increased Leydig cell number

small testis

testis degeneration

abnormal adrenal gland physiology

Availability

Mouse Genotype

Clcn2^tm1Mlv/Clcn2^tm1Mlv

Clcn2^tm1Tjj/Clcn2^tm1Tjj

Clcn2^em1Uis/Clcn2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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